My dog has a small sore on her ankle. It is not swollen or hot to the touch. Can I use Neosporin- or Polysporin- for humans on it?

Yes, for simple scrapes and abrasions.

It is okay to use human triple antibiotic ointment on simple scrapes or abrasions, but if your dog's skin lesion is more extensive or does not resolve itself within three to four days, you should have your dog checked by your veterinarian. Some skin lesions have an underlying cause that needs to be diagnosed in order to determine the treatment necessary to allow the wound to heal. In some cases what appears to be a superficial wound is actually a small puncture that is festering below the surface. If you find that the affected area becomes swollen, tender or reddened it needs the care of your veterinarian.